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Because powdered cascara sagrada is really the bark or outer covering of a tree, technically it does not belong under the classification of "herbs," per se, since true natural herbs are actually leaves and blades of grass. Nonetheless, like roots and flowers, bark such as dried rhamnus purshiana have long had their uses. In 1890, U.S. drug manufacturers abandoned the use of the European blackthorn berry in favor of cascara sagrada bark as the primary ingredient of over-the-counter laxatives. This continued until 2002, when the U.S. Food and Drug Administration banned its use in such medications.

Bulk herbs such as rhammus purshiana are usually harvested in the wild, after which they are dried and aged for a time - usually a year - before they are marketed as wholesale organic herbs. Like other bulk herbs, the effect of cascara sagrada bark can be harsh if used in its fresh, undiluted form, so it is best to use aged dried cascara sagrada bark.

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